Evolution GC-MS/MS TripleQuad
Keeping the original inert ion source, the true hyperbolic quadrupole and the highly sensitive HED detector provides the best possible basis for the next logical step in mass spectrometry: MS-MS. By adding a proprietary Ion Rail collision cell and another high precision quadrupole – serving as mass filter Q3 – the AGILENT MSD is easily upgraded to a triple quadrupole instrument, the CHROMTECH EVOLUTION. Imagine all the possibilities of MS/MS combined with the ruggedness and reliability of the AGILENT MSD 5973/75 series base instrument.
Function and Advantages of Triple Quadrupole MS/MS
A triple quadrupole mass spectrometer (QqQ) links two stages of mass analysis. The first quadrupole mass filter (Q1) pre-selects a precursor ion (“parent ion”) which is fragmented by collision with an inert gas in the RF-only collision cell (q2). The resulting product ions (“daughter ion”) are subsequently selected by the thirdquadrupole (Q3) mass filter.
Using Multiple Reaction Monitoring (MRM) is the most sensitive and selective technique to quantitate low levels of target compounds, especially in the presence of high background from sample matrix. Chemical background, usually present in single quad analysis (SIM) is almost completely eliminated.
Typical applications for the MS/MS technique are doping analysis, forensic science, drug testing, pesticide residues in food, biomarker analysis for oil exploration, dioxin trace analysis, etc. In essence, samples with heavy matrix.
